Immunosuppressive Therapy and Hepatitis B Virus Reactivation
نویسندگان
چکیده
منابع مشابه
Lamivudine therapy for prevention of immunosuppressive-induced hepatitis B virus reactivation in hepatitis B surface antigen carriers.
Viral reactivation in hepatitis B surface antigen (HBsAg) carriers undergoing immunosuppressive therapy is well documented. To evaluate the role of lamivudine prophylaxis in Hepatitis B virus (HBV) carriers treated with immunosuppression for nonhepatic disorders, we reviewed our experience between 1997 and 2000 at Hadassah University Hospital (Jerusalem, Israel). Controls were patients who were...
متن کاملhepatitis b reactivation during immunosuppressive therapy or cancer chemotherapy, management, and prevention: a comprehensive review
results it was found that the positive hepatitis b surface antigen (hbsag), the high baseline hbv dna level, the positive hepatitis b virus e antigen (hbeag), and an absent or low hepatitis b surface antibody (hbsab) titer prior to starting treatment are the most important viral risk factors. furthermore, rituximab, anthracycline, and different types of tnf-α inhibitors were identified as the h...
متن کاملReactivation of hepatitis B virus associated with chemotherapy and immunosuppressive agent.
Hepatitis B virus (HBV) reactivation after chemotherapy or immunosuppressive therapy is a serious cause of liver-related morbidity and mortality. The mechanism of HBV reactivation is still unclear, but it is believed due to the suppression of immune response hence increasing the viral load. No uniform diagnostic criteria are available, HBV reactivation can be confirmed by an increase in serum H...
متن کاملPreventing hepatitis B reactivation due to immunosuppressive drug treatments.
Reactivation of the hepatitis B virus (HBV) can cause severe liver injury resulting in jaundice, liver failure, and death.1 This outcome continues to occur in patients receiving immunosuppressive drug therapy (ISDT) despite the ability to identify persons at risk with readily available and inexpensive blood tests for hepatitis B surface antigen (HBsAg) and antibody to hepatitis B core antigen (...
متن کاملHepatitis B Reactivation During Immunosuppressive Therapy or Cancer Chemotherapy, Management, and Prevention: A Comprehensive Review
CONTEXT Due to the close relationship between the immune system and the hepatitis B virus (HBV) replication, it is essential to monitor patients with current or past HBV infection under any type of immunosuppression. Cancer chemotherapy, immunosuppressive therapies in autoimmune diseases, and immunosuppression in solid organ and stem cell transplant recipients are the major reasons for hepatiti...
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ژورنال
عنوان ژورنال: Viral Hepatit Dergisi
سال: 2016
ISSN: 1307-9441
DOI: 10.4274/vhd.48615